Dr. Chan is the founder of a multi-disciplinary design practice arQstudio Ltd and a co-founder of the architectural practice AMQ Ltd and the HK room in PMQ. Her social innovation idea, aTTempspace, won 2015 Techathon, which led to an IT startup in Science Park.

Before her entrepreneurial ventures, she was the Director of Design and Project in Hysan Development Co. Ltd from 2008 to August 2014, She led teams to complete the LEED and Beam Plus Platinum project, Hysan Place and a number of major asset enhancement projects in Lee Gardens area, Causeway Bay. Before joining Hysan, she was a design director in P&T Architects and Engineers Ltd. Her projects won many local and international awards, such as ULI Global Sustainability Award, AIA/ALA Library Award, DFA Best Design from Greater China Award, MIPIM Gold Award, HKIA Annual Awards, etc. She was also the recipient of Hong Kong Young Architect Award in 1993 and the winner of Tai O Twin Bridges Design Competition in 2013.

Apart from design works, she is an artist, curator and writer. She blogs at the platform ARSPIRE (http://arspire.blogspot.hk or www.arspire.com). Currently she is also a Director of the Hong Kong Architecture Centre.